I found that going from X to Y is more than just simply changing the settings in the ini file! Bugs/Quirks that work in X don't always work in Y (and vice versa) so watching the console/scanning the log files when you switch is essential to see all the things that fail! I'd say it's worth doing, but depending on how many regions and scripts you have, you may need to decide just how much downtime you are going to get as you fix all the compatibility issues.
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